Compile Data Set for Download or QSAR
maximum 50k data
Found 111 of ic50 data for polymerid = 10701
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497270(CHEMBL3347551)
Affinity DataIC50:  30nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of lithium dodecyl sulphate-stimulated ROS generation preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497271(CHEMBL3347550)
Affinity DataIC50:  30nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of lithium dodecyl sulphate-stimulated ROS generation preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50218664(CHEMBL5275943)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufuMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612720(CHEMBL5279528)
Affinity DataIC50:  520nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612719(CHEMBL5285816)
Affinity DataIC50:  910nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612714(CHEMBL5279646)
Affinity DataIC50:  990nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM318936(US10173988, Compound A)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human NOX2More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612709(CHEMBL5282245)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612711(CHEMBL5278688)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612712(CHEMBL5269753)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612718(CHEMBL5269857)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM318936(US10173988, Compound A)
Affinity DataIC50:  1.68E+3nMAssay Description:Cells: Human blood was purchased in buffy coat, prepared the same day for isolation of neutrophils, from Labjoy AB, Lund, Sweden. Blood components we...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612701(CHEMBL5266372)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612704(CHEMBL5266063)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612710(CHEMBL5290483)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612703(CHEMBL5269456)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612706(CHEMBL5283659)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612707(CHEMBL5287636)
Affinity DataIC50:  2.72E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612715(CHEMBL5287582)
Affinity DataIC50:  2.79E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612713(CHEMBL5271584)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612705(CHEMBL5291222)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612716(CHEMBL5270712)
Affinity DataIC50:  2.96E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612722(CHEMBL5268914)
Affinity DataIC50:  3.39E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612700(CHEMBL5287478)
Affinity DataIC50:  3.58E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612717(CHEMBL5268551)
Affinity DataIC50:  3.73E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)
Affinity DataIC50:  5.00E+3nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612721(CHEMBL5282886)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612702(CHEMBL5290730)
Affinity DataIC50:  5.66E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612723(CHEMBL5286033)
Affinity DataIC50:  6.33E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497263(CHEMBL3347554)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM65841(2-(trifluoromethyl)-10H-phenothiazine | SR-0100044...)
Affinity DataIC50:  9.00E+3nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM71623(3,5-bis(chloranyl)-N-[(E)-[4-(dimethylamino)phenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50612708(CHEMBL5277244)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497272(CHEMBL3347543)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM318939(US10173988, Compound D)
Affinity DataIC50:  1.50E+4nMAssay Description:Cells: Human blood was purchased in buffy coat, prepared the same day for isolation of neutrophils, from Labjoy AB, Lund, Sweden. Blood components we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50606914(CHEMBL5218591)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human NOX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM318940(US10173988, Compound inventive)
Affinity DataIC50:  1.60E+4nMAssay Description:Cells: Human blood was purchased in buffy coat, prepared the same day for isolation of neutrophils, from Labjoy AB, Lund, Sweden. Blood components we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM318937(US10173988, Compound B)
Affinity DataIC50:  1.70E+4nMAssay Description:Cells: Human blood was purchased in buffy coat, prepared the same day for isolation of neutrophils, from Labjoy AB, Lund, Sweden. Blood components we...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497271(CHEMBL3347550)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497271(CHEMBL3347550)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497262(CHEMBL3347492)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497273(CHEMBL3347583)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497265(CHEMBL3347503)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497257(CHEMBL3347502)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497270(CHEMBL3347551)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497270(CHEMBL3347551)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497262(CHEMBL3347492)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497259(CHEMBL3347542)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497268(CHEMBL3347491)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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